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Embryo Cryopreservation


Cryopreservation of Embryo

The process of preserving an embryo at an embryogenesis stage agreeing to pre-implantation is called Cryopreservation of embryos.

Indications

Some patients who fail to conceive after IVF Treatment may become pregnant using their preserved embryos without under going full IVF cycle. In case of successful pregnancy after IVF Treatment, they could return in future for additional pregnancy. Spare oocytes or embryos resulting from fertility treatments may be used for oocyte donation or embryo donation to another woman or couple, and embryos may be created, frozen and stored specifically for transfer and donation by using donor eggs and sperm.

Method

Embryo cryopreservation is done using vitrification  technique versus slow programmable freezing (SPF). Virification results in decreased risk of DNA damage than slow freezing.

Pregnancy Outcome and Determinants

Use of cryopreserved embryos doesn’t results with increase in birth defects or development abnormalities in intracytoplasmic sperm injection (ICSI).

In fact, pregnancy rates are increased following frozen embryo transfer, and perinatal outcomes are less affected, compared to embryo transfer in the same cycle as ovarian hyper stimulation was performed.