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PGS (Preimplantation Genetic Screening)


IVF

Overview

  • PGS is a genetic test performed on embryos to identify numerical chromosomal abnormalities (aneuploidy).
  • The test is performed on embryos before transfer to the uterus.
  • By analysing all embryos generated in an IVF treatment cycle those free of chromosomal aneuploidy can be selectively transferred.
  • As a result, the pregnancy rates per transfer are significantly increased and the miscarriage rates decreased.

Benefits

  • Increases pregnancy rates per transfer. Selecting normal embryos can increase the pregnancy chances after transfer.
  • Reduction in miscarriage rate In the general population, 25% of all clinical pregnancies end in miscarriage.
  • Increase in the likelihood of having a healthy baby Some pregnancies with chromosomal anomalies can give rise to the birth of baby with a serious illness.

Indications

  • Advanced maternal age: 35 years or above
  • Recurrent miscarriages: 2 or more miscarriages of unknown cause
  • Assisted reproduction cycles without pregnancy: 2 or more assisted reproduction cycles without pregnancy result
  • Male factor: Males with low sperm concentration, below 5 million per ml
  • Previous pregnancies with anomalies: 1 previous pregnancy with chromosome abnormality, especially in an assisted reproduction cycle