- 50% of miscarriages in the first trimester are caused by chromosomal abnormalities.
- For women undergoing assisted reproduction treatment this proportion is 60% and increases with the woman’s age.
- All 24 chromosomes are analysed to identify the reason for the pregnancy failure.
- The mother’s blood is taken to rule out any contamination in the foetal sample.
- Information from the POC test can help patients choose future reproductive options to ensure a healthy pregnancy.
- Results are obtained in >98% of cases.
- Results are available quickly as cell culture is not required.
- False negative results caused by maternal contamination can be ruled out.
- STR microsatellite (DNA fingerprinting) technology is used to identify the maternal or foetal origin of the material analysed.
- NGS has higher resolution than a conventional karyotype.
- Can be performed on twin pregnancies.
The POC test is suitable for:
- Women who have suffered a pregnancy loss.
- Women who have experienced recurrent miscarriages.
- Couples undergoing assisted reproduction treatment, as useful information to guide future treatment choices.