IUI

IUI

Intrauterine insemination (IUI) is done in order to facilitate fertilization through placement of sperm inside a female’s uterus. The IUI aim of increasing number of sperm that reaches the fallopian tubes resulting in increase chance of fertilization.

Intrauterine insemination (IUI) is done in order to facilitate fertilization through placement of sperm inside a female’s uterus. The IUI aim of increasing number of sperm that reaches the fallopian tubes resulting in increase chance of fertilization. Sperm required to reach and fertilize the egg gets an additional advantage from IUI. In comparison to in vitro fertilization IUI is a less invasive and a relatively cheap choice Sperm required to reach and fertilize the egg gets an additional advantage from IUI. In comparison to in vitro fertilization IUI is a less invasive and a relatively cheap choice.

How does IUI work?

The IUI procedure will then be performed at around the time of ovulation, after proper monitoring and indication that ovulation will occur soon. In the lab separation of semen from the seminal fluid is done by washing semen sample. The sperms are inserted directly into the uterus by the use of catheter. Possibility of conception increases as large numbers of sperm cells are placed in the uterus. Success Rate: Several factors determine the success of IUI. Success rates may extent to 20% per cycle if IUI procedure done each month dependent on multiple factors.

ICSI Work

Semen Preparation

Before IUI, it is necessary to remove seminal plasma to avoid contractions of the uterus caused by prostaglandins. For normal semen samples, it is unclear whether there is any advantage in separating the most active sperm before insemination or whether the entire population of sperm in the sample can be used to obtain similar results.
Quality of the Specimen

Quality of the Specimen

According to reports, if the semen sample contains a total of 10 million sperm, pregnancy rate will be reduced. About insemination samples, the recommended lower limit range from 3 million active sperm to 5 million, to 10 million.
Mode of Insemination

Mode of Insemination

Sperm suspension can be placed in the cervix, the uterus, the peritoneum or the Fallopian tube. It is guided by introducing a 0.2 – 0.5 ml sperm suspension into the uterus using a small catheter. With Fallopian tube sperm perfusion (FSP), the inseminating material is 4 ml, so with this large volume of fluid, material can not only fill the uterine cavity and Fallopian tubes, but some of the volume may even end up in the abdominal cavity. If semen sample is freezed, IUI is more suitable than intracervical insemination (ICI) the probability of live birth after six insemination cycles is 2-times higher.
Timing of Insemination

Timing of Insemination

Insemination can be performed at various time points around ovulation and can be performed once or many times. In most published studies, insemination is performed after 32 – 36h hCG administration. Given that the timing of insemination relative to ovulation is the key to the optimal success rate, few studies aim to find the optimal timing for insemination is quite surprising. A systematic review found that there was no difference in pregnancy rates for every two fertilized couples compared to a single fertilization
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