FET
Frozen Embryo Transfer
Frozen Embryo Transfer (FET) is a process where previously frozen embryos from a fresh IVF cycle are thawed and transferred into the woman’s uterus.
This method allows you to avoid a repeat cycle of hormonal stimulation and egg collection. The frozen embryo cycle can be done either naturally, with hormone preparation, or through ovulation induction, depending on individual needs.
Clinical Studies of Frozen Embryo Transfer (FET)
Research suggests that hormonal interventions may impact endometrial receptivity and pregnancy success. Studies indicate that FET cycles conducted without hormonal intervention might yield higher success rates. Currently, over 1,000 patients are enrolled in new multicenter randomized trials (Antarctic trials) to examine how natural vs. artificial FET cycles affect living costs, health outcomes, and adverse events. Although further research on older women and poor responders is needed, existing evidence supports that FET may provide safer pregnancy outcomes, shifting the burden of proof to those who advocate for fresh embryo transfer.
Intra Cytoplasmic Sperm Injection (ICSI)
(Define this term, e.g., a procedure where a single sperm is injected directly into an egg to assist with fertilization)
TSH Treatments
Treatment options to stabilize TSH levels vary depending on age, related conditions, and tolerance, including oral medication, radiation, or surgery.
FET Success Rates
A systematic review and meta-analysis of three randomized controlled trials, including 633 women, showed increased clinical pregnancy rates (CPR) and ongoing pregnancy rates for FET compared to fresh embryo transfers, with no significant difference in miscarriage rates. While more data is needed for women with poorer prognoses, early findings for women over 35 indicate promising results. However, a clearer comparison of live-birth rates and associated economic implications between fresh and frozen transfers is still pending.
Embryo Freezing/Cryopreservation
Cryopreservation, often used to preserve extra embryos after an IVF cycle, allows all embryos to be frozen for future FET cycles, also known as an “all-frozen” approach. Advances in cryopreservation, from slow freezing to rapid vitrification with cryoprotectants, have significantly increased embryo survival rates upon thawing, with studies showing over 95% survival. The vitrification method demonstrates higher success rates for ongoing pregnancies compared to slower freezing methods.
FAQ's
The success rate for frozen embryo transfer may vary from clinic to clinic. It can be as high as 65% or more, depending on the facility.
For more details about IVF treatment, contact Australian Concept at 0309 – 3332229 for expert care and guidance.
No, freezing embryos does not affect the IVF success rate or the quality of the embryos. In fact, it has the same (or even higher) success rate as fresh embryo transfer.
For more details about IVF treatment, contact Australian Concept at 0309 – 3332229 for expert care and guidance.
Some clinics transfer embryos quickly within 3-5 hours of thawing, while others wait up to 24 hours. The longer culture period allows embryos to recover from thawing before they are implanted.
For more details about IVF treatment, contact Australian Concept at 0309 – 3332229 for expert care and guidance.
FET is a relatively safe procedure. However, it can cause mild cramping, spotting, and discomfort.
For more details about IVF treatment, contact Australian Concept at 0309 – 3332229 for expert care and guidance.
To prepare the uterus for a Frozen Embryo Transfer, the doctor recommends hormonal shots that thicken the uterine lining, which improves the chances of the fertilized egg attaching to the endometrium.
For more details about IVF treatment, contact Australian Concept at 0309 – 3332229 for expert care and guidance.
