FET
Frozen Embryo Transfer (FET) is a process where previously frozen embryos from a fresh IVF cycle are thawed and transferred into the woman’s uterus.
This method allows you to avoid a repeat cycle of hormonal stimulation and egg collection. The frozen embryo cycle can be done either naturally, with hormone preparation, or through ovulation induction, depending on individual needs.
Research suggests that hormonal interventions may impact endometrial receptivity and pregnancy success. Studies indicate that FET cycles conducted without hormonal intervention might yield higher success rates. Currently, over 1,000 patients are enrolled in new multicenter randomized trials (Antarctic trials) to examine how natural vs. artificial FET cycles affect living costs, health outcomes, and adverse events. Although further research on older women and poor responders is needed, existing evidence supports that FET may provide safer pregnancy outcomes, shifting the burden of proof to those who advocate for fresh embryo transfer.
Intra Cytoplasmic Sperm Injection (ICSI)
(Define this term, e.g., a procedure where a single sperm is injected directly into an egg to assist with fertilization)
Treatment options to stabilize TSH levels vary depending on age, related conditions, and tolerance, including oral medication, radiation, or surgery.
A systematic review and meta-analysis of three randomized controlled trials, including 633 women, showed increased clinical pregnancy rates (CPR) and ongoing pregnancy rates for FET compared to fresh embryo transfers, with no significant difference in miscarriage rates. While more data is needed for women with poorer prognoses, early findings for women over 35 indicate promising results. However, a clearer comparison of live-birth rates and associated economic implications between fresh and frozen transfers is still pending.
Cryopreservation, often used to preserve extra embryos after an IVF cycle, allows all embryos to be frozen for future FET cycles, also known as an “all-frozen” approach. Advances in cryopreservation, from slow freezing to rapid vitrification with cryoprotectants, have significantly increased embryo survival rates upon thawing, with studies showing over 95% survival. The vitrification method demonstrates higher success rates for ongoing pregnancies compared to slower freezing methods.
Best IVF Center in Pakistan Australian Concept Group (ACG) is a group of companies operating since early 1998 with a primary focus on improving the lives of human beings. Infertility Clinic is one of ACG's main businesses and since its inception, ACG is proud to be the pioneer in offering world-class Infertility Treatment options across Pakistan
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