Roles In Males
In Males the Sertoli cells are induced by the FSH to secrete androgen-binding proteins (ABPs). Inhibin’s negative feedback mechanism on the anterior pituitary gland regulates its activity. The activation of Sertoli cells sustains spermatogenesis and the secretion of inhibin B is also stimulated.
Consequences In Males
In Males The primary spermatocytes are stimulated by the FSH to undergo the first division of meiosis to form secondary spermatocytes. The production of androgen-binding proteins by the Sertoli cells of the testes is enhanced by FSH which initiates spermatogenesis.
Roles In Females
In Females the FSH initiates the follicular growth by affecting the granulosa cells. The rise in inhibin B cause a decline in the FSH level in the late follicular phase. There is a slight rise in the FSH level at the end of the luteal phase that has its significance in starting the next ovulatory cycle.
Consequences In Females
In Females The follicle-stimulating hormone controls the menstrual cycles. The growth and recruitment of the immature follicles in the ovary are stimulated by the FSH.